FlowLac® 100
Premium spray-dried alpha-lactose monohydrate – Ph. Eur., USP-NF, JP, ChP
Spray-dried lactose, such as FlowLac®, is produced by spray-drying a fine-milled alpha-lactose monohydrate suspension, resulting in a porous, spherical morphology with smooth surface properties. This enhances flowability, making it ideal for direct compression in high-speed tableting operations. Unlike crystalline alpha-lactose monohydrate, spray-dried lactose monohydrate contains a certain amount of amorphous lactose, which enables plastic deformation during compaction and results in significantly improved tablet compactibility. The combination of amorphous and crystalline forms creates a synergistic effect, leading to superior binding properties and reduced tablet friability.
FlowLac® 100 is a standard spray-dried alpha-lactose monohydrate offering superior flowability and compactibility compared to other lactose grades. Its spherical particle morphology and balanced amorphous content provide excellent tableting performance, making it suitable for direct compression processes and formulations with poorly flowing active pharmaceutical ingredients.
Benefits
- Superior flowability
- Best in class compactibility
- Very low strain rate sensitivity (high speed compression)
- Smooth surface (glossy tablets)
- Fast disintegration times
Areas of Application
- Direct compression
- Continuous applications
- Formulations with poorly flowing API’s
- Capsule and sachet filling
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- Direct compression
- Continuous processing
- Spray-dried Lactose
- Oral Solid Dose
- Placebo tablet
- Low to medium dose DC formulation
- Formulation with poorly flowing API
- Capsule
- Tablet
- Sachet
25kg – Paper bag with PE-EVOH-PE inliner
18 months
Wasserburg am Inn, Germany
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Typical particle size distribution
Typical Product Data
- x10: 43 µm, x50: 133 µm, x90: 239 µm
- Span [(x90-x10)/x50]: 1.47
- Density bulk: 0.613 g/ml
- Density tapped: 0.699 g/ml
- Hausner Ratio: 1.14
- Carr’s Index: 12 %
Specified Product Data
Particle size distribution
Sieve Method: Air-jet sieving
- <32 µm: NMT 10%
- <100 µm: 20-45%
- <200 µm: NLT 80%
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