GranuLac® 200
Premium milled alpha-lactose monohydrate – Ph. Eur., USP-NF, JP, ChP
Milled alpha-lactose monohydrate is widely used in wet and dry granulation, where finer particles have proven to be beneficial for solid dosage formulations. With a narrow particle size distribution (PSD), defined surface properties, and controlled density, it allows for precise modulation of compactibility, compressibility, porosity, and segregation tendency. Its brittle nature ensures good binding properties, consolidating primarily by fragmentation, making it an ideal choice for tablet production.
GranuLac® 200 is a milled 200 mesh alpha-lactose monohydrate containing fine, sharp-edged lactose particles with cohesive powder properties that benefit wet and dry granulation processes. The brittle fracture mechanism during compaction process creates clean, unlubricated surfaces, improving overall compactibility. MEGGLE’s milled 200 mesh lactose grade is broadly utilized as diluent in dry and wet granulation by pharmaceutical producers worldwide.
Benefits
- Good compactibility
- Narrow particle size distribution
- Good blending properties
- High storage stability
- High batch-to-batch consistency
Areas of Application
- Dry granulation
- Wet granulation
- Blends, premixes, sachets, triturations
- Enhancement of flavours
- Media for fermentation
- Extrusion-spheronization
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- Wet granulation
- Dry granulation
- Dry blending / Trituration
- Milled Lactose
- Oral Solid Dose
- Placebo tablet
- Enhancement of flavours
- Extrusion-spheronization
- Media for Fermentation
- Capsule
- Sachet
- Tablet
25kg – Paper bag with PE-EVOH-PE inliner
36 months
- Wasserburg am Inn, Germany
- Le Sueur/Minnesota, USA
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Typical particle size distribution
Typical Product Data
- x10: 3 µm, x50: 28 µm, x90: 94 µm
- Span [(x90-x10)/x50]: 3.25
- Density bulk: 0.532 g/ml
- Density tapped: 0.844 g/ml
- Hausner Ratio: 1.59
- Carr’s Index: 37 %
Specified Product Data
Particle size distribution
Sieve Method: Air-jet sieving
- <32 µm: 45-75%
- <100 µm: NLT 90%
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