Cellactose® 80
Premium co-processed Excipient
75 % alpha-lactose monohydrate and 25 % powdered cellulose.
Co-processed excipients (CPEs) play a key role in modern pharmaceutical manufacturing by offering significantly improved functionality compared to conventional excipients. Through the physical combination of established substances – multifunctional particle systems are created with enhanced flowability, compactibility, and reduced sensitivity to lubricants. This leads to improved tablet uniformity and mechanical strength while reducing the need for additional formulation steps. Especially in direct compression, CPEs enable more efficient and robust tablet production, even with high drug loads or poorly compressible APIs. Since they are composed of pharmacopoeial-approved components, regulatory requirements are minimal, further increasing their appeal.

Cellactose® 80 is a co-processed excipient of 75 % alpha-lactose monohydrate and 25 % powdered cellulose, designed for direct compression. It offers excellent flowability, compactibility, and high adherence capacity, ensuring uniform content in low-dose formulations and enhanced tablet hardness in high-dose applications.
Benefits
- Excellent compactibility and flowability
- Perfectly suited for poorly compressible APIs (e. g. herbal extracts)
- High adherence capacity to API
- Ideal tablet surface for easy and economical coating
- High adherence capacity may prevent segregation and improves content uniformity
Areas of Application
- Direct compression
- Dry granulation (Roller compaction, slugging)
- Capsule filling
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- Dry granulation
- Direct compression
- Roller compaction
- Continuous processing
- Co-processed Excipients
- Oral Solid Dose
- Placebo tablet
- Low to high dose DC formulation
- Formulation with poorly flowing API
- Formulation with micronized API
- Capsule
- Tablet
20kg – Paper bag with PE-EVOH-PE inliner
36 months
Wasserburg am Inn, Germany
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Typical particle size distribution
Typical Product Data
- x10: 38 µm, x50: 167 µm, x90: 298 µm
- Span [(x90-x10)/x50]: 1.56
- Density bulk: 0.425 g/ml
- Density tapped: 0.532 g/ml
- Hausner Ratio: 1.25
- Carr’s Index: 20 %
Specified Product Data
Particle size distribution
Sieve Method: Air-jet sieving
- <32 µm: NMT 20%
- <160 µm: 35-65%
- <250 µm: NLT 80%
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