GranuLac® 230
Premium milled alpha-lactose monohydrate – Ph. Eur., USP-NF, JP, ChP
Milled alpha-lactose monohydrate is widely used in wet and dry granulation, where finer particles have proven to be beneficial for solid dosage formulations. With a narrow particle size distribution (PSD), defined surface properties, and controlled density, it allows for precise modulation of tabletability, compactibility, and compressibility. Finer GranuLac® grades and SorboLac® 400 typically result in tablets with higher tensile strength and faster disintegration. Its brittle nature ensures good binding properties, consolidating primarily by fragmentation, making it an ideal choice for tablet production. However, milled lactose exhibits limited flowability and should therefore be granulated prior to tableting whenever possible. Due to its excellent compression and blending properties, lactose is the most commonly used filler for granulation.
GranuLac® 230 is a milled alpha-lactose monohydrate grade containing fine, sharp-edged lactose particles that exhibit cohesive powder properties, making them ideal for wet and dry granulation processes. During compaction, brittle fracture results in clean, unlubricated surfaces, enhancing compactability.
Benefits
- Good compactibility
- Narrow particle size distribution
- Good blending properties
- High storage stability
- High batch-to-batch consistency
Areas of Application
- Dry granulation
- Wet granulation
- Blends, premixes, sachets, triturations
- Enhancement of flavours
- Media for fermentation
- Extrusion-spheronization
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- Wet granulation
- Dry granulation
- Dry blending / Trituration
- Milled Lactose
- Oral Solid Dose
- Placebo tablet
- Enhancement of flavours
- Extrusion-spheronization
- Media for Fermentation
- Capsule
- Sachet
- Tablet
25kg – Paper bag with PE-EVOH-PE inliner
24 months
Wasserburg am Inn, Germany
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Typical particle size distribution
Typical Product Data
- x10: 3 µm, x50: 19 µm, x90: 62 µm
- Span [(x90-x10)/x50]: 3.20
- Density bulk: 0.501 g/ml
- Density tapped: 0.768 g/ml
- Hausner Ratio: 1.54
- Carr’s Index: 35 %
Specified Product Data
Particle size distribution
Sieve Method: Air-jet sieving
- <63 µm: NLT 90%
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