InhaLac® 400
Premium fine milled DPI alpha-lactose monohydrate – Ph. Eur., USP-NF, JP, ChP
Fine milled DPI lactose further enhances aerodynamic performance, promoting efficient dispersion and reducing agglomeration in inhalation devices. Micronized DPI lactose, with an even smaller particle size, is particularly effective for modifying powder cohesion and achieving precise drug-carrier interactions, ensuring optimal deep lung deposition.
InhaLac® 400 – “the multitalent”. MEGGLE’s finest grades are used to tune DPI performance in tertiary blends. The addition of fines usually improves aerosolisation performance by enhancing the API detachment or co-agglomeration. InhaLac® 400 and InhaLac® 500 are both fine lactose grades produced under different milling conditions to achieve the desired particle size distribution (PSD). InhaLac® 500 is finer, with 90 % of particles smaller than ≤ 10 μm. InhaLac® 400 is slightly coarser with a typical median particle size of x50 = 8 μm.
Typical concentrations of fines ranges from a few percent up to 20 % for InhaLac® 400 and up to 10 % for InhaLac® 500. If the fine content is too high, flowability and further processing may be impaired.
Benefits
- High storage stability
- Highly controlled and homogenous powder characteristics
- Highest microbial quality including low endotoxins
Areas of Application
- InhaLac® 400 is a fine milled lactose suitable for use in pulmonary and nasal drug delivery.
Order your free sample!
- Dry Powder Inhalation
- Fine milled Lactose DPI
- Inhalation Lactose
- Inhalation
- Nasal
- Dry Powder Inhaler (DPI)
- Fines (DPI)
- Soft pallet formulations (DPI)
15kg – Carton box with aluminium laminated and PE-EVOH-PE inliner
24 months
Wasserburg am Inn, Germany
Downloads
Typical particle size distribution
Typical Product Data
- x10: 1.3 µm, x50: 8.0 µm, x90: 25.0 µm
- Span [(x90-x10)/x50]: 3.0
- % fines <5 µm: 38
- Density bulk: 0.35 g/ml
- Density tapped: 0.58 g/ml
- Hausner Ratio: 1.66
- Carr’s Index: 40 %
Specified Product Data
Particle size distribution
Sieve Method: Laser diffraction
- x10: 0.8-1.6
- x50: 4.0-11.0
- x90: 15.0-35.0
Do you have any questions or need a customised solution?