InhaLac® 70
Premium sieved alpha-lactose monohydrate for DPI applications – Ph.Eur., USP-NF, JP, ChP
Lactose for dry powder inhalation
InhaLac® suitable for use in pulmonary and nasal drug delivery.
MEGGLE’s InhaLac® portfolio offers a broad range of high-purity lactose grades specifically engineered for dry powder inhalation (DPI). With decades of expertise, we deliver consistent particle size distributions, excellent flow properties, and superior batch-to-batch uniformity – ensuring optimal performance in DPI formulations. Whether for originators or generics, MEGGLE is your trusted partner for tailored carrier solutions that meet global pharmacopeial standards.
InhaLac® – Sieved DPI Lactose
Sieved lactose monohydrate is a key excipient in dry powder inhalation (DPI) formulations, offering critical advantages that support consistent drug delivery and efficient production processes. Its well-defined and narrow particle size distribution ensures excellent flow properties and reliable dosing. Additionally, the tailored surface characteristics of sieved lactose enhance the interaction with active pharmaceutical ingredients (APIs), improving drug dispersion and lung deposition.
Key benefits of sieved lactose monohydrate in DPI formulations:
- Optimized particle size distribution for consistent flow and uniform blending
- Improved flowability and handling, minimizing segregation risks
- Enhanced drug delivery efficiency through better API adhesion and detachment
- High purity and compliance with global pharmacopeial standards (USP-NF, Ph. Eur., JP, ChP)
These properties make sieved lactose an ideal carrier for both originator and generic DPI products, supporting robust formulation performance and patient-centric drug delivery.
Portfolio – Sieved DPI Lactose
InhaLac® – Milled DPI Lactose
Milled lactose monohydrate is a critical excipient in dry powder inhalation (DPI) formulations, valued for its tailored particle size distribution and unique surface morphology. Its irregularly shaped particles contribute to improved powder flow and enhance the interaction with active pharmaceutical ingredients (APIs). These properties support efficient aerosolization and consistent delivery of medication to the lungs. Milled lactose is especially useful in customizing DPI formulations, either as a stand-alone carrier or in combination with other lactose grades.
Key benefits of milled lactose monohydrate in DPI formulations:
- Tailored particle size distribution for optimal performance across different inhaler types
- Enhanced flowability due to irregular particle morphology
- Improved drug dispersion and fine particle fraction through optimized surface interactions
- Flexible use in combination with other carriers to fine-tune formulation performance
- Full compliance with USP-NF, Ph. Eur., JP, ChP pharmacopeial standards
These characteristics make milled lactose monohydrate a versatile and reliable choice for high-performance DPI formulations, supporting both formulation stability and patient-centric drug delivery.
Portfolio – Milled DPI Lactose
InhaLac® – Fine milled DPI Lactose
Fine milled and micronized lactose monohydrate are specialized carrier grades used in dry powder inhalation (DPI) formulations to optimize drug delivery performance. Fine milled lactose offers a narrow particle size distribution and favorable flow properties, making it suitable for use as a primary or co-carrier in DPI systems. Micronized lactose, with its significantly smaller particle size, is typically used in ternary blends to improve the aerodynamic behavior of the formulation. By occupying high-energy binding sites on the surface of coarser carriers, micronized lactose facilitates better detachment of the active pharmaceutical ingredient (API), increasing the fine particle fraction (FPF) that reaches the lungs.
Key benefits of fine milled and micronized lactose monohydrate in DPI formulations:
- Controlled and narrow particle size distributions for consistent blending and flow
- Improved API dispersion through reduced cohesion and better particle detachment
- Enhanced fine particle fraction (FPF) in ternary blends for more efficient lung deposition
- Support for complex formulation designs, including both binary and ternary systems
- High microbiological quality and compliance with international pharmacopeial standards
These characteristics make fine milled and micronized lactose valuable tools for tailoring DPI formulations to specific device types and therapeutic requirements.
