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InhaLac® 500

Dry powder inhalers (DPIs) are widely used in pulmonary drug delivery. This is due to their advantages, such as ease of use, small size, portability and not needing breath-actuation coordination. In addition, they are propellant-free and therefore, environmentally friendly. Furthermore, as solid-particle formulations they are comparatively stable. Commonly, this dosage form contains a device, one or more APIs and an excipient, which improves powder handling during the manufacturing process. Properties, such as particle size are fundamental factors in the design of DPI formulations.

In DPI formulations the excipient not only acts as a filler, but also contributes to the performance of the DPI. A profound knowledge about the physico-chemical properties is a prerequisite to ensure the functionality and safety of the DPI. This implies an established and well-investigated production process.

MEGGLE’s InhaLac® grades are produced via crystallization and subsequent sieving, milling or micronization.

Shelf life / Retest:
12 months

Standard Packaging:
10 kg - Carton box with aluminium laminated Inliner
Particle size distribution
[Laser diffraction]

  • x10: -
  • x50: NMT 5 µm
  • x90: NMT 10 µm
Typical Values
  • Bulk Density [g/l]: 240
  • Tapped Density [g/l] : 370
  • Hausner factor: 1.54
  • Carrs index: 35 %
DPI Lactose_excipient inhalation_micronized_500 Mesh
Benefits
  • Highly controlled powder characteristics
  • Highest microbial quality including endotoxines
  • A broad spectrum of different sizes ranges
  • Tailor-made inhalation grades
  • Customized product specifications
Areas of Application
InhaLac® stands for a lactose, which is, in particular, suitable for use in pulmonary and nasal drug delivery.
Typical particle size distribution (PSD) ofsomething new
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Specification(s)
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